STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maddMAP-kinase activating death domain. (1672 aa)    
Predicted Functional Partners:
I3K566_ORENI
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.714
LOC100534578
Tumor necrosis factor b (TNF superfamily, member 2).
     
 0.695
rab27b
RAB27B, member RAS oncogene family.
     
 0.679
LOC100706684
Uncharacterized protein.
     
 0.679
rab27a
RAB27A, member RAS oncogene family.
     
 0.679
Mapkapk3
Mitogen-activated protein kinase-activated protein kinase 3.
      
 0.643
LOC100690604
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.633
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
      
 0.628
trib2
Tribbles pseudokinase 2.
      
 0.617
I3K0A7_ORENI
DENN/MADD domain containing 1A.
    
 
0.617
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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