rnf185 protein (Oreochromis niloticus) - STRING interaction network

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Score

rnf185

Ring finger protein 185. (172 aa)

Predicted Functional Partners:

derl1

0.767

sel1l

0.744

cftr

0.712

limk2

0.695

uba52

0.684

ENSONIP00000047919

0.661

LOC100709255

0.641

LOC100692599

0.641

derl2

0.634

LOC100692885

0.634

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	LOC100692599	ENSONIP00000047919	ENSONIP00000073250	Ubiquitin B.	ER lipid raft associated 1.	0.621
ENSONIP00000047919	LOC100692885	ENSONIP00000047919	ENSONIP00000017529	Ubiquitin B.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.626
ENSONIP00000047919	LOC100709255	ENSONIP00000047919	ENSONIP00000031281	Ubiquitin B.	ER lipid raft associated 2.	0.621
ENSONIP00000047919	cftr	ENSONIP00000047919	ENSONIP00000038035	Ubiquitin B.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.535
ENSONIP00000047919	derl1	ENSONIP00000047919	ENSONIP00000009190	Ubiquitin B.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.661
ENSONIP00000047919	derl2	ENSONIP00000047919	ENSONIP00000014579	Ubiquitin B.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.626
ENSONIP00000047919	rnf185	ENSONIP00000047919	ENSONIP00000077231	Ubiquitin B.	Ring finger protein 185.	0.661
ENSONIP00000047919	sel1l	ENSONIP00000047919	ENSONIP00000000911	Ubiquitin B.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.656
ENSONIP00000047919	uba52	ENSONIP00000047919	ENSONIP00000016035	Ubiquitin B.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.997
LOC100692599	ENSONIP00000047919	ENSONIP00000073250	ENSONIP00000047919	ER lipid raft associated 1.	Ubiquitin B.	0.621
LOC100692599	LOC100692885	ENSONIP00000073250	ENSONIP00000017529	ER lipid raft associated 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.552
LOC100692599	LOC100709255	ENSONIP00000073250	ENSONIP00000031281	ER lipid raft associated 1.	ER lipid raft associated 2.	0.611
LOC100692599	cftr	ENSONIP00000073250	ENSONIP00000038035	ER lipid raft associated 1.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.529
LOC100692599	derl1	ENSONIP00000073250	ENSONIP00000009190	ER lipid raft associated 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.660
LOC100692599	derl2	ENSONIP00000073250	ENSONIP00000014579	ER lipid raft associated 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.552
LOC100692599	rnf185	ENSONIP00000073250	ENSONIP00000077231	ER lipid raft associated 1.	Ring finger protein 185.	0.641
LOC100692599	sel1l	ENSONIP00000073250	ENSONIP00000000911	ER lipid raft associated 1.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.690
LOC100692885	ENSONIP00000047919	ENSONIP00000017529	ENSONIP00000047919	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin B.	0.626
LOC100692885	LOC100692599	ENSONIP00000017529	ENSONIP00000073250	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER lipid raft associated 1.	0.552
LOC100692885	LOC100709255	ENSONIP00000017529	ENSONIP00000031281	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER lipid raft associated 2.	0.552