STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B4119_0502Hypothetical protein; Cysteinyl-tRNA synthetase related protein; Belongs to the UPF0374 family. (177 aa)    
Predicted Functional Partners:
B4119_0501
Hypothetical protein; Lipid A export ATP-binding/permease protein MsbA.
       0.775
B4119_1325
Hypothetical protein; Alternate gene name: yoxG.
 
    0.671
cysS
Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
      0.658
B4119_0503
FIG00673238: hypothetical protein.
       0.620
mltG
Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
     0.581
B4119_1222
FIG006438: hypothetical protein; Belongs to the UPF0223 family.
  
     0.549
B4119_0055
Cell division protein DivIC.
  
     0.505
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
  
     0.494
B4119_0868
Adenylate cyclase.
  
     0.493
queA
Hypothetical protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
     0.463
Your Current Organism:
Parageobacillus caldoxylosilyticus
NCBI taxonomy Id: 81408
Other names: ATCC 700356, Bacillus sp. BGSC W9A59, Bacillus sp. BGSC W9A68, DSM 12041, Geobacillus caldoxylosilyticus, Geobacillus caldoxylosilyticus (Ahmad et al. 2000) Fortina et al. 2001, NBRC 107762, P. caldoxylosilyticus, Saccharococcus caldoxylosilyticus, Saccharococcus caldoxylosilyticus Ahmad et al. 2000, strain S1812
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.