Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SDZ91479.1Na+-driven multidrug efflux pump. (454 aa)    
Predicted Functional Partners:
SEA46070.1
Putative efflux protein, MATE family.
  
     0.771
SEA46037.1
MatE protein.
  
     0.765
SEA30381.1
Putative efflux protein, MATE family.
  
     0.745
SEA47449.1
Putative efflux protein, MATE family.
  
     0.739
SEA86025.1
Putative efflux protein, MATE family.
  
     0.590
SEA39778.1
Putative efflux protein, MATE family.
  
     0.573
SEA28869.1
Putative efflux protein, MATE family.
  
     0.570
SDZ91427.1
Diguanylate cyclase (GGDEF) domain-containing protein.
       0.501
SDZ91453.1
Two-component system, OmpR family, sensor histidine kinase KdpD.
       0.501
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.482
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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