Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SDZ92203.1Biotin transport system substrate-specific component. (178 aa)    
Predicted Functional Partners:
ecfT
Energy-coupling factor transport system permease protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 0.782
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.722
SEA70883.1
Energy-coupling factor transport system permease protein.
  
 0.714
SEA66781.1
Biotin transport system substrate-specific component.
  
     0.711
ecfA-2
Energy-coupling factor transport system ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.707
ecfA
Energy-coupling factor transport system ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.694
SEA14091.1
Cobalt/nickel transport system ATP-binding protein; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
   
 0.639
SEA61274.1
Cobalt/nickel transport system ATP-binding protein.
   
 0.639
SEA14065.1
Cobalt/nickel transport system permease protein.
  
 0.592
SEA61250.1
Cobalt/nickel transport system permease protein.
  
 0.592
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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