Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SDZ89088.1Haloacid Dehalogenase Superfamily Class (subfamily) IIA. (266 aa)    
Predicted Functional Partners:
SDZ89048.1
Glycerol-1-phosphate dehydrogenase [NAD(P)+].
 
 
 0.825
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
  0.770
xylB
Xylulokinase.
  
    0.765
SEA79099.1
IMP dehydrogenase.
    
  0.756
cinA
Competence/damage-inducible protein cinA; Belongs to the CinA family.
   
 
  0.749
cmk
Cytidylate kinase.
  
 
  0.595
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
    
  0.583
SDZ92647.1
Glycerol-1-phosphate dehydrogenase [NAD(P)+].
 
 
 0.518
SEA82173.1
Purine nucleosidase.
    
 0.473
dut
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
  0.470
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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