Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SDZ93781.1DNA-binding transcriptional regulator, XRE-family HTH domain. (251 aa)    
Predicted Functional Partners:
SEA79973.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
     
 0.685
SEA30703.1
Mannose-6-phosphate isomerase, cupin superfamily.
  
 0.536
SDZ93806.1
Hypothetical protein.
     
 0.520
SDZ93831.1
Helix-turn-helix domain-containing protein.
       0.516
SDZ93859.1
AAA domain-containing protein.
  
    0.504
SEA72747.1
Chorismate mutase.
  
 
 0.504
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.464
SDZ90703.1
Zn-dependent peptidase ImmA, M78 family.
  
 
 0.403
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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