Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SDZ90268.1L-iditol 2-dehydrogenase. (352 aa)    
Predicted Functional Partners:
SEA25416.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.881
SEA51271.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.805
SDZ90128.1
PTS system, fructose-specific IIC component.
    
  0.800
SDZ90247.1
Threonine dehydrogenase.
 
    
0.792
SDZ89356.1
PTS system IIA component, Glc family.
   
 
 0.785
SEA83275.1
PTS system IIA component, Glc family /PTS system IIB component, Glc family /PTS system IIC component, Glc family.
   
 
 0.785
SDZ90297.1
Multimeric flavodoxin WrbA.
       0.775
SEA28746.1
PTS system D-fructose-specific IIA component (F1P-forming), Frc family /PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-forming), Frc family.
  
 
 0.772
SEA59512.1
PTS system, N-acetylgalactosamine-specific IIA component.
  
 
 0.762
SEA59323.1
L-threonine ammonia-lyase.
   
 
 0.741
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
Server load: low (38%) [HD]