Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SDZ98634.1Dihydrolipoamide dehydrogenase. (455 aa)    
Predicted Functional Partners:
SEA29219.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.988
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.967
SEA29186.1
Pyruvate dehydrogenase E1 component beta subunit.
 
 0.964
SEA59792.1
Glycine cleavage system H protein.
 
 
 0.944
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.933
SDZ98603.1
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
    
 0.893
SEA29158.1
Pyruvate dehydrogenase E1 component alpha subunit.
 
 
 0.876
SEA25416.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.869
SDZ98564.1
Methylene-tetrahydrofolate reductase C terminal.
    
 0.867
SEA80019.1
2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).
  
 0.829
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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