Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEA07392.1Dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (372 aa)    
Predicted Functional Partners:
SEA07361.1
tRNA (adenine22-N1)-methyltransferase.
  
 0.986
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.840
sigA
RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.835
folE
GTP cyclohydrolase I.
    
 0.822
SEA08572.1
Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
  0.820
SEA14700.1
L-threonine O-3-phosphate decarboxylase.
  
  
 0.808
hisC
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.808
SEA07274.1
FMN adenylyltransferase /riboflavin kinase; Belongs to the ribF family.
       0.784
SEA51886.1
ADP-ribose pyrophosphatase YjhB, NUDIX family.
    
  0.783
SEA07211.1
Phosphoesterase RecJ domain-containing protein.
 
     0.781
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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