Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEA34594.1Putative MFS transporter, AGZA family, xanthine/uracil permease. (454 aa)    
Predicted Functional Partners:
SEA13216.1
Phosphoribosylformylglycinamidine synthase.
  
  
 0.852
purE
5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.575
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.509
SEA34570.1
Hypothetical protein.
       0.485
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
  
  
 0.483
SEA34544.1
Hypothetical protein.
       0.467
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
 0.461
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
  
 0.453
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
  
  
 0.451
SEA38193.1
Gluconolactonase.
     
 0.440
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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