Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEA50440.1Threonine synthase. (503 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.999
SEA50409.1
Homoserine dehydrogenase.
 
 0.990
SEA59323.1
L-threonine ammonia-lyase.
  
 
 0.938
SEA50488.1
Chorismate mutase; Belongs to the UPF0735 family.
 
  
 0.908
SEA50381.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.888
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
   
 0.869
SEA58810.1
Diaminopropionate ammonia-lyase.
  
 
 0.847
SDZ90628.1
L-threonine aldolase.
    
 0.827
SEA06570.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.771
SEA06601.1
Aspartate kinase.
  
 
 0.771
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
Server load: medium (48%) [HD]