Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEA69454.1Pyruvate phosphate dikinase. (873 aa)    
Predicted Functional Partners:
SEA25416.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.921
SEA79973.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
  
 
 0.881
SEA51271.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.848
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.820
SEA16677.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.810
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.810
SEA09443.1
Malate dehydrogenase (oxaloacetate-decarboxylating).
   
 
 0.807
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.805
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.787
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.781
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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