Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEA76788.1AraC-type DNA-binding protein. (420 aa)    
Predicted Functional Partners:
SEA25416.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.789
SEA76835.1
Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain.
 
     0.777
SEA76814.1
Hypothetical protein.
       0.741
SEA35421.1
Helix-turn-helix domain-containing protein.
    
  0.732
SEA81832.1
Two-component system, response regulator YesN.
    
  0.732
SEA74172.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
  
  0.726
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.724
SEA81846.1
Histidine kinase.
 
  
  0.684
SEA35396.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  
  0.667
SEA19219.1
Ligand-binding sensor domain-containing protein.
     
  0.657
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
Server load: medium (44%) [HD]