Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEA83275.1PTS system IIA component, Glc family /PTS system IIB component, Glc family /PTS system IIC component, Glc family. (740 aa)    
Predicted Functional Partners:
SDZ89356.1
PTS system IIA component, Glc family.
 
0.995
SEA36100.1
Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 0.993
SEA28746.1
PTS system D-fructose-specific IIA component (F1P-forming), Frc family /PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-forming), Frc family.
 
 
 0.992
SDZ91658.1
PTS system, sucrose-specific IIC component.
 0.991
SDZ89462.1
PTS system maltose-specific IIB component, Glc family /PTS system maltose-specific IIC component, Glc family.
 
0.979
SDZ89406.1
Glucokinase.
  
 0.978
SEA21224.1
Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.
  
 0.978
SEA53578.1
Glucokinase.
  
 0.978
SDZ90128.1
PTS system, fructose-specific IIC component.
  
 
 0.975
SDZ91630.1
Beta-fructofuranosidase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 
 0.974
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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