Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEA86158.1DNA-binding response regulator, LytR/AlgR family. (197 aa)    
Predicted Functional Partners:
SEA74172.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.846
SEA35396.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.815
SEA81846.1
Histidine kinase.
 
 
 0.814
SEA83529.1
LytTr DNA-binding domain-containing protein.
  
     0.673
SEA83492.1
GHKL domain-containing protein.
 
 
 0.592
SEA74155.1
Transcriptional regulatory protein, C terminal.
  
     0.574
SEA72839.1
5TMR of 5TMR-LYT.
 
 0.571
SEA13188.1
Signal transduction histidine kinase.
    
 0.487
SDZ91379.1
PAS domain S-box-containing protein.
    
 0.485
SEA12246.1
Signal transduction histidine kinase.
    
 0.485
Your Current Organism:
Eubacterium aggregans
NCBI taxonomy Id: 81409
Other names: DSM 12183, E. aggregans, Eubacterium aggregans Mechichi et al. 2000, strain SR12
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