Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ddi2DNA-damage inducible protein 2. (907 aa)    
Predicted Functional Partners:
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.901
psma2
Proteasome endopeptidase complex.
   
 
 0.874
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.872
rad23a
RAD23 homolog A, nucleotide excision repair protein a.
   
 
 0.863
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.863
LOC102302180
Uncharacterized protein.
   
 
 0.863
LOC102314666
Ubiquitin-like domain-containing protein.
   
 
 0.838
KIF5B
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
     
  0.834
ube3c
Ubiquitin protein ligase E3C.
   
 
 0.834
cct2
Chaperonin containing TCP1, subunit 2 (beta).
   
   0.823
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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