STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
huwe1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (3770 aa)    
Predicted Functional Partners:
ENSHBUP00000022543
DUF908 domain-containing protein.
 
     0.930
LOC102314666
Ubiquitin-like domain-containing protein.
   
 0.915
rps27a
Ribosomal protein S27a.
   
 0.896
ddit4
DNA-damage-inducible transcript 4.
    
   0.869
ENSHBUP00000006170
Uncharacterized protein.
    
 
 0.865
LOC102314370
MCL1 apoptosis regulator, BCL2 family member b.
    
 
 0.865
ubb
Ubiquitin-like domain-containing protein.
    
 0.861
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.861
trip12
Thyroid hormone receptor interactor 12.
   
 
0.806
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.751
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.