STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pde6gPhosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b. (87 aa)    
Predicted Functional Partners:
LOC102314661
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 0.992
LOC102304204
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 0.991
pde5a
Phosphodiesterase.
   
 0.979
pde6a
Phosphodiesterase.
   
 0.968
LOC102302197
Phosphodiesterase.
   
 0.964
pde6c
Phosphodiesterase.
   
 0.951
LOC102292070
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.930
LOC102298597
Phosphodiesterase.
    
 0.926
LOC102312728
Guanylate cyclase.
   
 
 0.923
pde11a
Phosphodiesterase.
   
 0.923
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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