Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ankrd16Ankyrin repeat domain 16. (371 aa)    
Predicted Functional Partners:
pnisr
PNN-interacting serine/arginine-rich protein.
   
 
 0.796
rbm17
RNA binding motif protein 17.
    
 
 0.754
nsmce4a
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
    
 
 0.733
isca2
Iron-sulfur cluster assembly 2.
     
 0.720
fbh1
F-box DNA helicase 1.
     
 0.685
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.657
traf7
TNF receptor-associated factor 7.
    
  0.620
mars1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 0.603
tsen54
TSEN54 tRNA splicing endonuclease subunit.
      
 0.593
TMEM14C
Transmembrane protein 14Cb.
      
 0.580
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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