STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sh3kbp1Uncharacterized protein. (745 aa)    
Predicted Functional Partners:
ENSHBUP00000002891
UBA domain-containing protein.
    
 0.954
rps27a
Ribosomal protein S27a.
    
  0.939
LOC102305228
Uncharacterized protein.
    
 0.938
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.938
cblc
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.938
LOC102314666
Ubiquitin-like domain-containing protein.
    
  0.915
LOC102291569
SH3-domain GRB2-like 1b.
   
0.909
sh3gl1
SH3-domain GRB2-like 1a.
   
 
0.900
sh3gl2
SH3 domain containing GRB2 like 2a, endophilin A1.
   
0.897
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.893
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.