STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHBUP00000014062Uncharacterized protein. (398 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
    
 0.962
ENSHBUP00000007607
Reverse transcriptase domain-containing protein.
 
     0.845
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
 
 0.789
ENSHBUP00000005659
Uncharacterized protein.
 
     0.778
ENSHBUP00000000773
Reverse transcriptase domain-containing protein.
 
     0.694
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.650
rpa1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.650
lin54
Lin-54 DREAM MuvB core complex component.
    
 0.632
ercc4
Excision repair cross-complementation group 4.
    
  0.630
lin9
Lin-9 DREAM MuvB core complex component.
    
 0.627
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.