STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pak6Non-specific serine/threonine protein kinase. (698 aa)    
Predicted Functional Partners:
ENSHBUP00000012412
Uncharacterized protein.
    
 0.991
LOC102297644
Intersectin 2b.
    
 0.991
CDC42
Cell division cycle 42.
   
 0.948
LOC102311613
Cell division cycle 42.
   
 0.948
LOC102301399
Rho guanine nucleotide exchange factor (GEF) 7a.
    
 0.934
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.934
LOC102306701
Rho guanine nucleotide exchange factor (GEF) 7b.
    
 0.934
nck2
Cytoplasmic protein.
    
 0.926
nck1
Cytoplasmic protein.
    
 0.926
LOC102294469
Uncharacterized protein.
   
 0.905
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.