STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nab2NGFI-A binding protein 2 (EGR1 binding protein 2). (498 aa)    
Predicted Functional Partners:
egr2
Early growth response 2b.
   
 0.907
egr3
Early growth response 3.
   
 0.828
ENSHBUP00000001169
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
   
 0.823
chd4
Uncharacterized protein.
   
 0.751
LOC102291041
Chromodomain helicase DNA binding protein 4a.
   
 0.751
aire
Autoimmune regulator.
   
 0.751
chd5
Chromodomain helicase DNA binding protein 5.
   
 0.751
LOC102310951
Chromodomain helicase DNA binding protein 3.
   
 0.751
phf21a
PHD finger protein 21Ab.
   
 0.668
PHF21B
PHD finger protein 21B.
   
 0.668
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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