STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mthfs5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (200 aa)    
Predicted Functional Partners:
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
 0.948
ftcd
Formimidoyltransferase cyclodeaminase.
    
 0.934
ENSACLP00000009069
Methenyltetrahydrofolate synthetase domain containing.
     
 0.925
mthfd1
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.
   
 0.919
ENSACLP00000023470
THF_DHG_CYH domain-containing protein.
   
 0.919
mtfmt
Mitochondrial methionyl-tRNA formyltransferase.
  
 
 0.917
ENSACLP00000028179
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.
   
 0.913
LOC113034258
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
    
 0.910
LOC113033300
Uncharacterized protein.
    
 0.910
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.902
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.