Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113034610Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)    
Predicted Functional Partners:
spr
Sepiapterin reductase b.
     
 0.878
ptges3
Prostaglandin E synthase 3a (cytosolic).
    
 0.863
dhfr
Dihydrofolate reductase.
    
 0.863
dcxr
Dicarbonyl/L-xylulose reductase.
   
 0.860
LOC113009224
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2.
  
 0.854
ENSACLP00000041285
Prostaglandin E synthase.
     
 0.852
pts
6-pyruvoyltetrahydropterin synthase.
    
 0.851
ENSACLP00000032492
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
    
  0.844
ENSACLP00000009717
UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.
    
  0.842
ENSACLP00000000787
Prostaglandin E synthase 2-like; Belongs to the GST superfamily.
     
 0.839
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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