STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asic2Acid-sensing (proton-gated) ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (561 aa)    
Predicted Functional Partners:
LOC113007707
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a.
    
 0.714
nedd4
NEDD4 E3 ubiquitin protein ligase a.
    
 0.714
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
    
 0.714
hecw2
Uncharacterized protein.
    
 0.714
ENSACLP00000010443
Si:ch211-188f17.1.
    
 0.714
stoml1
Stomatin (EPB72)-like 1.
    
 0.705
SMURF2
E3 ubiquitin-protein ligase.
    
  0.623
wwp2
E3 ubiquitin-protein ligase.
    
  0.623
smurf1
E3 ubiquitin-protein ligase.
    
  0.623
wwp1
WW domain containing E3 ubiquitin protein ligase 1.
    
  0.623
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.