STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fahFumarylacetoacetase. (418 aa)    
Predicted Functional Partners:
hgd
Homogentisate 1,2-dioxygenase.
  
 
 0.959
gstz1
Glutathione S-transferase zeta 1; Belongs to the GST superfamily.
  
 
 0.946
LOC113030206
Malate synthase-like.
  
 
 0.935
ENSACLP00000041514
Fumarylacetoacetate hydrolase domain containing 1.
     
 0.926
FAHD2A
Fumarylacetoacetate hydrolase domain containing 2A.
     
 0.908
ENSACLP00000002706
Fumarate hydratase.
  
 0.906
LOC113015012
Uncharacterized protein; Belongs to the GST superfamily.
  
 
 0.903
LOC113014538
Glutathione S-transferase rho; Belongs to the GST superfamily.
  
 
 0.903
sdha
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 
 0.895
metap1d
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
    
 0.889
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.