Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gsapGamma-secretase activating protein. (870 aa)    
Predicted Functional Partners:
RPS27A
Ribosomal protein S27a.
   
  0.914
ENSACLP00000009777
WDFY family member 4.
   
 0.895
ENSACLP00000010328
Uncharacterized protein.
   
 0.895
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.855
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.836
LOC113007350
Amyloid beta (A4) precursor protein b.
    
 
 0.799
APP
Amyloid beta precursor protein.
    
 
 0.799
ENSACLP00000037094
Im:7152348.
    
 0.777
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.764
ripk4
Receptor-interacting serine-threonine kinase 4.
    
  0.760
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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