STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000001068Cleavage stimulation factor, 3' pre-RNA, subunit 2. (528 aa)    
Predicted Functional Partners:
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
  
 0.999
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
    
 0.999
LOC113024099
FIP1 like 1b (S. cerevisiae).
   
 0.992
sympk
Symplekin.
   
 0.990
cpsf4
Cleavage and polyadenylation specific factor 4.
   
 0.990
clp1
Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]
   
 0.990
cpsf1
Cleavage and polyadenylation specific factor 1.
   
 0.988
WDR33
WD repeat domain 33.
    
 0.987
ENSACLP00000021431
Cleavage and polyadenylation specific factor 3.
   
 0.981
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.981
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.