Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
skiV-ski avian sarcoma viral oncogene homolog a. (715 aa)    
Predicted Functional Partners:
LOC113025730
Mothers against decapentaplegic homolog.
    
 0.986
ENSACLP00000022602
Mothers against decapentaplegic homolog.
    
 0.986
LOC113014376
Mothers against decapentaplegic homolog.
    
 0.986
LOC113033624
Mothers against decapentaplegic homolog.
    
 0.986
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.983
ENSACLP00000010348
Nuclear receptor corepressor 1.
   
 0.982
ncor2
Nuclear receptor corepressor 2.
   
 0.981
ENSACLP00000018602
SIN3 transcription regulator family member Ab.
   
 0.974
sin3a
SIN3 transcription regulator family member Aa.
   
 0.974
haus5
SIN3 transcription regulator family member B.
   
 0.970
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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