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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gneGlucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (763 aa)    
Predicted Functional Partners:
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
    
 0.958
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1.
   
 
 0.937
LOC113025209
UDP-N-acetylglucosamine pyrophosphorylase 1, like 1.
   
 
 0.937
ENSACLP00000000392
AFP-like domain-containing protein.
     
 0.912
LOC113023911
N-acetylneuraminic acid synthase b.
     
 0.912
ENSACLP00000000466
Ice-structuring protein; Lowers the blood freezing point. Contributes to protect fish blood from freezing at subzero sea water temperatures. Binds to nascent ice crystals and prevents further growth. Belongs to the type-III AFP family.
     
 0.912
LOC113023912
N-acetylneuraminic acid synthase b.
     
 0.912
LOC113023913
N-acetylneuraminic acid synthase b.
     
 0.912
hoga1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
    
 0.904
npl
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family.
    
 0.904
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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