Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
p2rx2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (415 aa)    
Predicted Functional Partners:
p2rx1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.902
LOC113024806
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.899
p2rx5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.890
ENSACLP00000035782
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.890
p2rx4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.887
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
     
 0.875
ENSACLP00000012724
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
     
 0.866
grin1
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
     
 0.866
grin3b
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
     
 0.858
LOC113029489
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.798
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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