Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113022570Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (482 aa)    
Predicted Functional Partners:
creb5
Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.
    
  0.971
ENSACLP00000036881
CREB binding protein a.
   
 0.959
LOC113020749
CREB binding protein b.
   
 0.959
LOC113014499
Uncharacterized protein.
    
  0.938
LOC113026110
JunE proto-oncogene, AP-1 transcription factor subunit.
   
 0.925
ENSACLP00000018137
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.925
LOC113036079
Mitogen-activated protein kinase.
   
 0.922
LOC113021131
E1A binding protein p300 b.
   
 0.922
LOC113027597
E1A binding protein p300 a.
   
 0.922
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.912
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.