Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prss56Serine protease 56; Belongs to the peptidase S1 family. (887 aa)    
Predicted Functional Partners:
tmem98
Transmembrane protein 98.
      
 0.851
mfrp
Membrane frizzled-related protein.
    
 
 0.726
ENSACLP00000014986
Olfactory receptor.
    
 
 0.677
nepro
Nucleolus and neural progenitor protein.
      
 0.676
ctdp1
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
      
 0.656
mettl11b
Methyltransferase like 11B.
      
 0.655
ppp1r32
Protein phosphatase 1, regulatory subunit 32.
    
 
 0.625
ENSACLP00000018221
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
      
 0.608
znf644
Zinc finger protein 644a.
    
 
 0.607
ENSACLP00000038796
Zinc finger protein 644b.
    
 
 0.607
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (18%) [HD]