Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000001307Matrix metallopeptidase 1. (474 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.877
mmp9
Matrix metallopeptidase 9.
   
 0.866
LOC113018838
Matrix metallopeptidase 14a (membrane-inserted).
   
  0.820
LOC113034822
Heparin-binding EGF-like growth factor a.
    
 0.803
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.798
edn1
Endothelin 1.
     
 0.792
LOC113022221
Cytochrome b-245, alpha polypeptide.
     
 0.786
ncf4
Neutrophil cytosolic factor 4.
     
  0.785
ncf1
Neutrophil cytosolic factor 1.
     
  0.785
LOC113020696
TIMP metallopeptidase inhibitor 2b.
   
 0.774
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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