Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tspan6Tetraspanin. (250 aa)    
Predicted Functional Partners:
pick1
Protein interacting with prkca 1.
    
 0.680
ENSACLP00000002578
SH2 domain-containing protein.
      
 0.662
met
MET proto-oncogene, receptor tyrosine kinase.
    
  0.606
LOC113022284
Macrophage stimulating 1 receptor a.
    
  0.606
mst1r
Macrophage stimulating 1 receptor b.
    
  0.606
tspan31
Tetraspanin 31; Belongs to the tetraspanin (TM4SF) family.
   
  
 0.522
dhrs7b
Dehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.496
ttc1
Tetratricopeptide repeat domain 1.
      
 0.493
LOC113027041
Zgc:123278.
    
 
 0.489
tsg101
Tumor susceptibility 101a.
    
 
 0.489
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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