Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000001347TLE family member 5, transcriptional modulator. (191 aa)    
Predicted Functional Partners:
ENSACLP00000021267
Transcription factor 7.
    
 0.908
ENSACLP00000032642
Lymphoid enhancer-binding factor 1.
    
 0.908
ENSACLP00000011542
Transcription factor 7 like 2.
    
 0.837
ENSACLP00000015078
Transcription factor 7 like 1b.
    
 0.837
ENSACLP00000017134
HMG box domain-containing protein.
    
 0.837
ENSACLP00000022686
Recombination signal binding protein for immunoglobulin kappa J region-like.
    
 0.837
ENSACLP00000036974
X-linked inhibitor of apoptosis.
    
  0.801
tbx20
T-box transcription factor 20.
    
 
 0.798
LOC113014899
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.778
hdac8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.778
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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