STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113029200Forkhead box I3b. (392 aa)    
Predicted Functional Partners:
suox
Sulfite oxidase.
     
 0.796
sgk3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.655
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.624
cdc25b
Rhodanese domain-containing protein.
   
 0.593
LOC113027513
Retinoblastoma binding protein 4, like.
   
 0.582
LOC113011815
Retinoblastoma binding protein 4.
   
 0.582
LOC113014472
WD_REPEATS_REGION domain-containing protein.
   
 0.582
mocs3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
  0.555
LOC113023444
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
     
 0.549
sting1
Transmembrane protein 173.
    
  0.539
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.