Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC113008860Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor. (1001 aa)    
Predicted Functional Partners:
RELN
Reelin.
    
 0.973
mylip
Myosin regulatory light chain interacting protein a.
    
 0.948
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.943
ENSACLP00000029644
Low density lipoprotein receptor adaptor protein 1b.
    
 0.922
dab1
DAB adaptor protein 1a.
    
 0.894
LOC113010063
DAB adaptor protein 1b.
    
 0.894
dab2
DAB adaptor protein 2.
    
 0.858
LOC113014738
Low density lipoprotein receptor adaptor protein 1a.
    
 0.849
ENSACLP00000041064
Apolipoprotein Eb.
    
 0.828
ENSACLP00000013261
Si:dkey-19b23.8.
    
  0.824
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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