Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rap1gapRAP1 GTPase activating protein. (780 aa)    
Predicted Functional Partners:
LOC113008802
Uncharacterized protein.
    
 0.945
LOC113021951
Uncharacterized protein.
    
 0.945
LOC113006695
DIRAS family GTPase 1.
    
 0.780
RAP2A
RAP2A, member of RAS oncogene family.
    
 0.780
LOC113012107
DIRAS family, GTP-binding RAS-like 1b.
    
 0.780
LOC113007449
RAP2C, member of RAS oncogene family.
    
 0.780
LOC113024026
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
    
 0.700
LOC113012815
Rap guanine nucleotide exchange factor (GEF) 3.
   
 0.631
clvs2
Clavesin 2.
      
 0.614
LOC113023559
SH3 and PX domains 2Aa.
      
 0.614
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.