Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1275 aa)    
Predicted Functional Partners:
LOC113030159
Estrogen-related receptor alpha.
   
 0.997
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 0.995
PPARG
Peroxisome proliferator activated receptor gamma.
    
 0.993
PPARA
Peroxisome proliferator-activated receptor alpha b.
    
 0.993
nrf1
Nuclear respiratory factor 1.
    
 0.990
ppara
Peroxisome proliferator-activated receptor alpha a.
    
 0.977
tfam
Transcription factor A, mitochondrial.
    
 0.967
sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.952
ENSACLP00000018657
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.942
ENSACLP00000015184
BUD31 homolog.
   
 0.938
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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