STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pitrm1Pitrilysin metallopeptidase 1. (1025 aa)    
Predicted Functional Partners:
grpel1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 
 0.919
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
   0.891
dld
Dihydrolipoyl dehydrogenase.
   
 
 0.877
LOC113007350
Amyloid beta (A4) precursor protein b.
    
 
 0.875
APP
Amyloid beta precursor protein.
    
 
 0.875
suclg2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
   0.871
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound; Belongs to the peptidase M24B family.
   
 
 0.859
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; Belongs to the peptidase M24B family.
   
 
 0.859
pmpcb
Peptidase (mitochondrial processing) beta; Belongs to the peptidase M16 family.
   
 
 0.845
ENSACLP00000029372
Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase.
     
 0.836
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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