Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000001569Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (343 aa)    
Predicted Functional Partners:
asah1
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
   
 
 0.976
ENSACLP00000025365
Neutral ceramidase.
    
 0.967
cers5
Ceramide synthase 5.
    
 0.952
ENSACLP00000031002
Ceramide synthase 4a.
    
 0.951
cers1
Ceramide synthase 1.
    
 0.951
LOC113014620
Ceramide synthase 2a.
    
 0.946
ENSACLP00000017287
Ceramide synthase 6.
    
 0.942
LOC113031460
Sphingosine kinase 2.
    
 0.939
degs1
Delta(4)-desaturase, sphingolipid 1.
   
 
 0.938
degs2
Delta(4)-desaturase, sphingolipid 2.
   
 
 0.938
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.