STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf7Interferon regulatory factor 7. (452 aa)    
Predicted Functional Partners:
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.938
tbk1
TANK-binding kinase 1.
   
 0.937
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.937
ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.931
LOC113028042
Protein kinase domain-containing protein.
    
 0.929
LOC113019278
Interferon regulatory factor 3.
  
  
0.927
irak1
Interleukin-1 receptor-associated kinase 1.
    
 0.922
LOC113011147
TRIF-NTD domain-containing protein.
    
 0.914
LOC113034514
Protein kinase domain-containing protein.
    
 0.908
ENSACLP00000036881
CREB binding protein a.
    
 0.903
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.