Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdzrn4PDZ domain containing ring finger 4. (813 aa)    
Predicted Functional Partners:
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.899
ENSACLP00000037094
Im:7152348.
    
 0.887
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.827
ENSACLP00000018312
Baculoviral IAP repeat containing 6.
   
 0.781
det1
DET1 partner of COP1 E3 ubiquitin ligase.
    
 0.727
RPS27A
Ribosomal protein S27a.
    
 0.709
lrit3
Info leucine-rich repeat, immunoglobulin-like and transmembrane domains 3a.
    
 0.694
ecsit
ECSIT signalling integrator.
    
 0.671
tradd
Tnfrsf1a-associated via death domain.
    
 0.661
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
    
 0.659
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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