Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)    
Predicted Functional Partners:
ENSACLP00000000986
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.999
pole4
Polymerase (DNA-directed), epsilon 4, accessory subunit.
    
 0.999
ENSACLP00000020901
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
 0.999
chrac1
Chromatin accessibility complex subunit 1.
    
 0.999
BAZ1A
Bromodomain adjacent to zinc finger domain 1A.
    
 0.993
ENSACLP00000010605
DNA polymerase.
   
 0.990
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
    
 0.990
ENSACLP00000017593
Polymerase (DNA directed), delta 2, regulatory subunit.
   
 0.989
nfyc
Nuclear transcription factor Y, gamma.
    
 0.987
dr1
Down-regulator of transcription 1.
   
 
 0.987
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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