STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrasHRas proto-oncogene, GTPase a. (189 aa)    
Predicted Functional Partners:
ENSACLP00000033310
Neurofibromin 1b.
    
 0.966
LOC113033717
A-Raf proto-oncogene, serine/threonine kinase.
  
 0.965
braf
B-Raf proto-oncogene, serine/threonine kinase.
  
 0.965
ENSACLP00000008120
RAS p21 protein activator (GTPase activating protein) 1a.
   
 0.952
rassf5
Ras association domain family member 5.
    
 0.950
plce1
Phospholipase C, epsilon 1.
    
 0.926
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.922
ralbp1
RalA binding protein 1.
    
 0.922
ENSACLP00000006489
Son of sevenless homolog 1 (Drosophila).
    
 0.921
LOC113010568
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.914
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.