Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113028240Gamma-synuclein; Belongs to the synuclein family. (119 aa)    
Predicted Functional Partners:
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.958
sncaip
Synuclein, alpha interacting protein.
    
 0.879
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
    
 0.877
sncb
Beta-synuclein; Belongs to the synuclein family.
   
 
 0.863
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
    
 0.831
psmc6
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
    
  0.812
ndufa9
NADH:ubiquinone oxidoreductase subunit A9a.
     
 0.801
ndufb6
NADH:ubiquinone oxidoreductase subunit B.
    
 0.800
psmb1
Proteasome subunit beta.
    
  0.789
psma1
Proteasome subunit alpha type.
    
  0.789
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (38%) [HD]