Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
YES1Tyrosine-protein kinase. (551 aa)    
Predicted Functional Partners:
ENSACLP00000018204
Protein tyrosine phosphatase receptor type C.
   
 0.931
LOC113021728
Ig-like domain-containing protein.
   
 0.925
grb2
Growth factor receptor-bound protein 2b.
    
 0.916
ENSACLP00000013202
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.908
LOC113023653
Catenin (cadherin-associated protein), delta 1.
    
 0.901
CTNND1
Catenin delta 1.
    
 0.901
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.894
LOC113012164
Tyrosine-protein kinase.
   
 0.891
fyn
Tyrosine-protein kinase.
   
 0.891
pgr
Progesterone receptor.
    
 0.888
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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